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Protective effect of circulating epinephrine within the physiological range on the airway response to inhaled histamine in non-asthmatic subjects".

Nebivolol and bucindolol, which have both β-blocking activity and vasodilator properties, improve left ventricular performance during long-term therapy.

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Vascular endothelial growth factor blockade prevents the beneficial effects of β-blocker therapy on cardiac function, angiogenesis and remodeling in heart failure.

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Patients with poor prognosis and life-threatening disease, such as malignant tumor, or such medical history within 5 years before the registration day.

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